Research Approach
My research is built on three interconnected pillars, all driving toward the central goal of understanding factors that impact patient outcomes and healthcare delivery.
Full Academic Works
Peer-Reviewed Publications
Ghoshal S, Silva SD, Liu DS, Flowers M, Sullivan M, Birch CM, Hedequist DJ, Hresko TM, Hogue G. Utility of Early Postoperative Clinic Imaging Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. Accepted, in proof in Spine (2025).
Ghoshal S, Sorel W, Roberts M, Chen AF. Impact of Tibiofemoral Compartment Gaps in Robotic Total Knee Arthroplasty on Patient Reported Outcomes. Accepted, in proof in Journal of Surgical Orthopaedic Advances (2025).
Ghoshal S, Silva SD, Liu DS, Flowers KM, Sullivan ML, Birch CM, Hedequist DJ, Hresko MT, Hogue GD. Utility of routine postoperative imaging following posterior spinal fusion for AIS. Spine Deform. 2025 Jul 18. doi: 10.1007/s43390-025-01149-1. Epub ahead of print. PMID: 40679702.
Ghoshal S, King AH, Pang M, Hood CM, Sodickson AD, Gee MS, Lev MH, Harris MB, Succi MD. Trends in Computed Tomography Utilization Among Emergency Department Patients with Foot and Ankle Trauma. J Foot Ankle Surg. 2025 Apr 15:S1067-2516(25)00117-6. doi: 10.1053/j.jfas.2025.04.007. PMID: 40246140.
Ghoshal S, Harary J, Jay JF, Al-Nassir Z; BWH PROMs Workgroup; Chen AF. Evaluating Patient-Reported Outcome Measure Collection and Attainment of Substantial Clinical Benefit in Total Joint Arthroplasty Patients. J Arthroplasty. 2024 Nov 23:S0883-5403(24)01259-2. doi: 10.1016/j.arth.2024.11.044. PMID: 39586411.
Ghoshal S, Liimakka AP, Harary J, Al-Nassir Z; BWH PROMs Workgroup; Chen AF. Effect of Race and Socioeconomic Status on the Attainment of Substantial Clinical Benefit on Patient-Reported Outcome Measures Following Total Joint Arthroplasty. J Arthroplasty. 2024 Oct 29:S0883-5403(24)01156-2. doi: 10.1016/j.arth.2024.10.116. Epub ahead of print. PMID: 39477035.
Smith ACW, Ghoshal S, Centanni SW, Heyer MP, Corona A, Wills L, Andraka E, Lei Y, O'Connor RM, Caligiuri SPB, Khan S, Beaumont K, Sebra RP, Kieffer BL, Winder DG, Ishikawa M, Kenny PJ. A master regulator of opioid reward in the ventral prefrontal cortex. Science. 2024 Jun 7;384(6700):eadn0886. doi: 10.1126/science.adn0886. Epub 2024 Jun 7. PMID: 38843332; PMCID: PMC11323237.
Ghoshal S, Stovall N, King AH, Miller AS, Harris MB, Succi MD. Orthopedic Surgery Volume Trends During the COVID-19 Pandemic and Postvaccination Era: Implications for Healthcare Planning. J Arthroplasty. 2024 Aug;39(8):1959-1966.e1. doi: 10.1016/j.arth.2024.03.028. Epub 2024 Mar 19. PMID: 38513749.
Rigney GH, King AH, Chung J, Ghoshal S, Jain A, Shi Z, Razak S, Hirsch JA, Lev MH, Buch K, Succi MD. Trends in non-focal neurological chief complaints and CT angiography utilization among adults in the emergency department. Intern Emerg Med. 2024 Oct;19(7):2005-2013. doi: 10.1007/s11739-024-03569-9. Epub 2024 Mar 21. PMID: 38512433.
Miller AS, Beagles CB, Kaur MN, Marano AA, Hu S, Ghoshal S, Dey T, Coon D, Succi MD. Temporary Declines and Demand Resurgence: Gender-Affirming Surgery Volume and Complication Trends During and After the COVID-19 Pandemic. Aesthetic Plast Surg. 2024 Sep;48(17):3520-3529. doi: 10.1007/s00266-024-04243-3. Epub 2024 Jul 11. PMID: 38992249.
Ghoshal S, Salazar C, Duggan J, Howell C, Chen AF, Shah VM. Assessment of Patient Satisfaction and Outcomes After Outpatient Joint Arthroplasty in Academic Medical Centers. Arthroplast Today. 2023 Nov 10;24:101246. doi: 10.1016/j.artd.2023.101246. PMID: 38205059; PMCID: PMC10776316.
Cheng D, Ghoshal S, Zattra O, Flash M, Lang M, Liu R, Lev MH, Hirsch JA, Saini S, Gee MS, Succi MD. Trends in oncological imaging during the COVID-19 pandemic through the vaccination era. Cancer Med. 2023 Apr;12(8):9902-9911. doi: 10.1002/cam4.5678. Epub 2023 Feb 12. PMID: 36775966; PMCID: PMC10166903.
Succi MD, Ghoshal S, Cheng D, Alvarez C, Bredella MA. A Scalable Mentoring Web Platform Deployed in a Large Academic System: Pilot Implementation. J Am Coll Radiol. 2023 Sep;20(9):928-932. doi: 10.1016/j.jacr.2023.01.011. Epub 2023 Mar 31. PMID: 37003309.
Ghoshal S, Rigney G, Cheng D, Brumit R, Gee MS, Hodin RA, Lillemoe KD, Levine WC, Succi MD. Institutional Surgical Response and Associated Volume Trends Throughout the COVID-19 Pandemic and Postvaccination Recovery Period. JAMA Netw Open. 2022 Aug 1;5(8):e2227443. doi: 10.1001/jamanetworkopen.2022.27443. PMID: 35980636; PMCID: PMC9389350.
Virji AZ, Cheloff AZ, Ghoshal S, Nagle B, Guo TZ, Lev MH, Raja AS, Gee MS, Succi MD. Analysis of self-initiated visits for cervical trauma at urgent care centers and subsequent emergency department referral. Clin Imaging. 2022 Nov;91:14-18. doi: 10.1016/j.clinimag.2022.08.007. Epub 2022 Aug 11. PMID: 35973271.
Rigney GH, Ghoshal S, Mercaldo S, Cheng D, Parks JJ, Velmahos GC, Lev MH, Raja AS, Flores EJ, Succi MD. Assessing the Relationship Between Race, Language, and Surgical Admissions in the Emergency Department. West J Emerg Med. 2023 Feb 1;24(2):141-148. doi: 10.5811/westjem.2022.10.57276. PMID: 36976591; PMCID: PMC10047742.
Smith ACW, Jonkman S, Difeliceantonio AG, O'Connor RM, Ghoshal S, Romano MF, Everitt BJ, Kenny PJ. Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions. Nat Commun. 2021 Aug 25;12(1):5121. doi: 10.1038/s41467-021-25460-3. PMID: 34433818; PMCID: PMC8387469.
Book Chapters
Ghoshal S, Shah VM. Preoperative Femoral Evaluation and Classification of Failure. In: Smith EL, Bono JV, eds. Revision Total Hip Arthroplasty. Pages 101-106. Springer; 2025. doi:10.1007/978-3-031-83959-7_12.
Published Abstracts
Ghoshal S, Ishmam M, Kenny P, Kenny P, Smith ACW. Identification of Novel Brain Regions Underlying Reinstatement to Oxycodone Seeking. ACNP 62nd Annual Meeting: Poster Abstracts P501 – P753. Neuropsychopharmacol. 48 (Suppl 1), 355–495 (2023). https://doi.org/10.1038/s41386-023-01757-3
Smith ACW, Ghoshal S, Winder D, Kenny P. A " Master Regulator" of Opioid Reward and Aversion in the Ventromedial Prefrontal Cortex. ACNP 60th Annual Meeting: Poster Abstracts P551 - P830. Neuropsychopharmacology. 2021 Dec;46(Suppl 1):369-518. doi: 10.1038/s41386-021-01238-5. PMID: 34857906; PMCID: PMC8637058.
Smith ACW, Centanni S, Ghoshal S, Winder D, Kenny PJ. The Dorsal Peduncular Cortex is a Cortical Master of Opioid Withdrawal. ACNP 59th Annual Meeting: Poster Session II. Neuropsychopharmacology. 2020 Dec;45(Suppl 1):170-277. doi: 10.1038/s41386-020-00891-6. PMID: 33279935; PMCID: PMC7735200.
Smith ACW, Centanni S, Ghoshal S, Winder D, Kenny PJ. Identification of the Dorsal Peduncular Area as a Highly Novel Regulator of Opioid Reward. ACNP 58th Annual Meeting: Poster Session III. Neuropsychopharmacology. 2019 Dec;44(Suppl 1):385-538. doi: 10.1038/s41386-019-0547-9. PMID: 31801974; PMCID: PMC6957926.
Podium Presentations (Selected)
Ghoshal S, Silva SD, Liu DS, Flowers M, et al. Utility of Early Postoperative Clinic Imaging Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. Scoliosis Research Society (SRS) 2025 Annual Meeting. Charlotte, NC, Sep 2025.
Ghoshal S, Friend T, Gustin M, Farid A, et al. Operative and Nonoperative Treatment of Lateral Compression Pelvic Fractures: A Cost-Effectiveness Analysis. Danish Orthopedic Society Congress Meeting 2025. Copenhagen, Denmark, Nov 2024.
Ghoshal S, Friend T, Gustin M, Farid A, et al. Operative and Nonoperative Treatment of Lateral Compression Pelvic Fractures: A Cost-Effectiveness Analysis. Harvard Orthopedic Trauma Research Conference. Boston, MA, May 2024.
Ghoshal S, Liimakka A, Sorel W, Roberts MS, et al. Impact of Tibiofemoral Compartment Gaps on Patient Reported Outcomes Following Robotic Total Knee Arthroplasty. 2024 Northeastern Arthroplasty Conference. Providence, RI, Mar 2024. (Awarded 2nd Place, Best Presentation)
Ghoshal S, Rigney G, Cheng D, Succi MD. Surgical Volume Trends throughout the COVID-19 Pandemic and Post-Vaccination Recovery. Mass General Brigham Aubrey O. Hampton Conference 2022. Boston, MA, Mar 2022.
Ghoshal S, Smith ACW, Kenny PJ. Role of the Dorsal Peduncular Cortex in the Control of Oxycodone Mediated Withdrawal, Aversion, and Pain Desensitization. Hunter College Undergraduate Research Conference 2020. New York, NY, May 2020.
Poster Presentations (Selected)
Ghoshal S, Friend T, Gustin M, Farid A, et al. Operative and Nonoperative Treatment of Lateral Compression Pelvic Fractures: A Cost-Effectiveness Analysis. Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). San Diego, CA, Mar 2025.
Ghoshal S, Harary J, Al-Nassir Z, Jay JF, et al. Evaluating Patient-Reported Outcome Measure Collection and Attainment of Substantial Clinical Benefit in Total Joint Arthroplasty Patients. Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). San Diego, CA, Mar 2025.
Ghoshal S, Flowers M, Baier A, Sullivan M, Hogue GD. Utility of Routine Postoperative Imaging following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis (AIS). 18th International Congress on Early Onset Scoliosis (ICEOS). Scottsdale, AZ, Nov 2024.
Ghoshal S, Flowers M, Baier A, Sullivan M, Hogue GD. Utility of Routine Postoperative Imaging following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis (AIS). Harvard Medical School Soma Weiss Research Conference. Boston, MA, Mar 2024.
Ghoshal S, Pang M, King AH, Sodickson AD, Gee MS, Lev MH, Harris MB, Succi MD. Trends in Computed Tomography Utilization Among Emergency Department Patients with Foot and Ankle Trauma. American Society of Emergency Radiology (ASER) 2023 Annual Meeting. San Diego, CA, Oct 2023.
Ghoshal S, Pang M, King AH, Sodickson AD, Gee MS, Lev MH, Harris MB, Succi MD. Trends in Computed Tomography Utilization Among Emergency Department Patients with Foot and Ankle Trauma. Harvard Orthopedic Trauma Research Conference. Boston, MA, May 2023.
Ghoshal S, Salazar C, Duggan J, Howell C, Chen AF, Vivek SM. Assessment of Patient Satisfaction and Outcomes Following Outpatient Joint Arthroplasty in Academic Medical Centers. 2023 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). Las Vegas, NV, Mar 2023.
Ghoshal S, Sorel W, Roberts MS, Chen AF. Impact of Tibiofemoral Compartment Gaps on Patient Reported Outcomes Following Robotic Total Knee Arthroplasty. 2023 Combined Mass General Brigham Orthopedic Research Retreat. Somerville, MA, Oct 2023.
Ghoshal S, Salazar C, Duggan J, Howell C, Chen AF, Vivek SM. Assessment of Patient Satisfaction and Outcomes Following Outpatient Joint Arthroplasty in Academic Medical Centers. 2022 Discover Brigham Research Conference. Boston, MA, Oct 2022.
Ghoshal S, Reiner D, Shaham Y. Role of orbitofrontal cortex in relapse to fentanyl seeking after food choice-induced voluntary abstinence. National Institutes of Health (NIH) Summer Research Conference. Bethesda, MD, Aug 2019.
Ghoshal S, Reiner D, Shaham Y. Role of orbitofrontal cortex in relapse to fentanyl seeking after food choice-induced voluntary abstinence. National Institute on Drug Abuse (NIDA) Summer Research Conference. Baltimore, MD, Aug 2019. (Awarded Best Poster Presentation)
Ghoshal S, Smith ACW, Kenny PJ. Brain Habit Center Regulates New Learning: Role for D1- and D2-MSNs. Annual Biomedical Research Conference for Minority Students (ABRCMS). Indianapolis, IN, Nov 2018. (Awarded Outstanding Presentation Award)
Ghoshal S, Smith ACW, Kenny PJ. Brain Habit Center Regulates New Learning: Role for D1- and D2-MSNs. Icahn School of Medicine's Undergraduate Research Symposium. New York, NY, Sep 2018.